Acrylic acids and derivatives
Matrix Scientific 2,2,2-TRIFLUOROETHYL ACRYL-25G
2, 2,2-Trifluoroethyl acrylate, 99%; 25g,C5H5F3O2, MFCD00000444, mw 154.09, [407-47-6]
Medchemexpress LLC HY-N0029 10mg Medchemexpress, Forsythoside B CAS:81525-13-5 Purity:>98%
Medchemexpress, HY-N0029 10mg Forsythoside B CAS:81525-13-5 Forsythoside B is a phenylethanoid glycoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha , IL-6 , IκB and modulate NF-κB . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC KW-2478 819812-04-9 50mg
KW-2478 (CAS 819812-04-9) is a potent non-ansamycin inhibitor of heat shock protein 90 (Hsp90) Unlike traditional Hsp90 inhibitors such as 17-AAG KW-2478 exhibits improved aqueous solubility and reduced hepatotoxicity In multiple myeloma cell models KW-2478 induces degradation of Hsp90 client proteins and leads to downregulation of IgH translocation products including FGFR3 c-Maf and cyclin D1 thereby inhibiting cell proliferation and promoting apoptosis Additionally KW-2478 reduces levels of Cdk9 and phosphorylated 4E-BP1 further suppressing oncogenic transcriptional regulators This compound is a valuable tool for studying Hsp90-mediated pathways and evaluating therapeutic strategies in hematological malignancies
Medchemexpress LLC (Z)-Ligustilide | 81944-09-4 | 190.24 | 20 MG
(Z)-Ligustilide, extracted from Ligusticum chuanxiong Hort, exhibits antimicrobial and antifungal activity. It functions by inhibiting fatty acid uptake and esterification, suggesting its potential as a therapeutic agent for nonalcoholic fatty liver disease (NAFLD). This compound also reactivates ERα, demonstrates epigenetic regulation, and is utilized in studies concerning tamoxifen-resistant breast cancer.
- Antimicrobial and antifungal properties
- Inhibits fatty acid uptake and esterification
- Potential therapeutic for nonalcoholic fatty liver disease (NAFLD)
- Reactivates ERα
- Exhibits epigenetic regulation
- Used in studies of tamoxifen-resistant breast cancer
eMolecules 92-61-5 | Scopoletin | Apollo Scientific | MFCD00006872 | 192.170 | C10H8O4 | 0.000 | COc1cc2ccc(=O)oc2cc1O | 1g | 562451991
Scopoletin | Apollo Scientific | 92-61-5 | MFCD00006872 | 192.170 | C10H8O4 | 0.000 | COc1cc2ccc(=O)oc2cc1O | 1g | 562451991
Medchemexpress LLC Mivotilate (standard) | 130112-42-4 | 99.6% | 330.45 g/mol | C12H14N2O3S3 | 25 MG
Mivotilate is a research-grade small-molecule activator of the aryl hydrocarbon receptor (AhR) with reported hepatoprotective activity. It is supplied as a purified analytical standard for laboratory use and is intended for in vitro research and analytical applications.
- Potent, nontoxic activator of the aryl hydrocarbon receptor.
- Reported hepatoprotective activity in preclinical studies.
- High purity suitable for analytical and research use.
- Molecular weight 330.45 g/mol; formula C12H14N2O3S3.
- Available in small, research-oriented pack sizes.
Medchemexpress LLC Kavain | 3155-48-4 | 100 MG
Kavain is a class of kavalactone isolated from *Piper methysticum*, which has anxiolytic properties in animals and humans. It positively modulates γ-Aminobutyric acid type A (GABAA) receptor. In vitro, Kavain positively modulates all GABAA receptors regardless of subunit composition, with a greater enhancement at α4β2δ than at α1β2γ2L GABAARs. Its modulatory effect is not affected by flumazenil, indicating it does not enhance GABAARs via the classical benzodiazepine binding site.
- Isolated from *Piper methysticum*
- Exhibits anxiolytic properties
- Positively modulates γ-Aminobutyric acid type A (GABAA) receptors
- Modulatory effect not affected by flumazenil
AA BLOCKS LLC Ingenol mebutate | 75567-37-2 | 430.5 g/mol | 1MG
Ingenol mebutate | 75567-37-2 | 430.5 g/mol | 1MG
Apexbio Technology LLC ITD 1 1099644-42-4 5mg
ITD-1 (CAS 1099644-42-4) is a selective inhibitor of transforming growth factor beta (TGF ) signaling TGF plays a critical role in early cardiac development particularly during the formation of endocardial cushions which give rise to cardiac valves ITD-1 promotes the degradation of the TGF type II receptor thereby modulating TGF -mediated pathways In vitro studies have demonstrated that ITD-1 specifically enhances mesodermal differentiation into cardiomyocytes from embryonic stem cells without promoting differentiation into vascular smooth muscle or endothelial cells ITD-1 serves as a valuable tool for investigating mesoderm and cardiac lineage specification in stem cell research
Medchemexpress LLC γ-Oryzanol | 11042-64-1 | 99.66% | 500 MG
γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. It significantly inhibits the activities of DNMT1 and DNMT3a.
- Potent DNA methyltransferases inhibitor.
- Significantly inhibits DNMT1 activity (IC50=3.2 μM).
- Significantly inhibits DNMT3a activity (IC50=22.3 μM).
eMolecules 75567-37-2 | Medchem Express | Ingenol Mebutate | 1mg | 446273206 | HY-B0719 | MFCD22683801 | 430.541 | C25H34O6
Medchem Express | Ingenol Mebutate | 1mg | 446273206 | HY-B0719 | 75567-37-2 | MFCD22683801 | 430.541 | C25H34O6
Enzo Life Sciences Parthenolide (50 mg). CAS: 20554-84-1
Sesquiterpene lactone. Widely used as an herbal remedy for arthritis and migraine. Has anti-inflammatory, antisecretory and spasmolytic activity. Specifically inhibits activation of NF-κB by preventing the degradation of IκBα and IκBβ. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs. Inhibits tubulin carboxypeptidase (TCP) activity. Alternative name: (1aR-[1aR*,4E,7aS*,-10aS*,-10bR*])-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclo deca[1,2-b]furan-9(1aH)-one. Purity: ≥97% (HPLC, TLC). Solubility: Soluble in DMSO (100mg/ml), dichloromethane (50mg/ml) or 100% ethanol (20mg/ml). Long Term Storage: -20°C.
eMolecules 2206-89-5 | 2-CHLOROETHYL ACRYLATE | AstaTech | MFCD00045292 | 134.560 | C5H7ClO2 | 95.000 | ClCCOC(=O)C=C | 1g | 718059713
2-CHLOROETHYL ACRYLATE | AstaTech | 2206-89-5 | MFCD00045292 | 134.560 | C5H7ClO2 | 95.000 | ClCCOC(=O)C=C | 1g | 718059713
Medchemexpress LLC HY-N0919 5mg Medchemexpress, Yangonin CAS:500-62-9 Purity:>98%
Medchemexpress, HY-N0919 5mg Yangonin CAS:500-62-9 Yangonin exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC50 and a Ki of 1.79 ± 0.53 μM and 0.72±0.21 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Monastrol | 329689-23-8 | MFCD00813077 | 99.9% | 292.35 g/mol | C14H16N2O3S | 100 MG
Monastrol is a cell-permeable small-molecule inhibitor of the mitotic kinesin Eg5, used in cell biology and mitosis research to perturb spindle dynamics and study chromosome segregation. It displays an IC50 of 14 μM against Eg5 and is provided as a high-purity research reagent for in vitro and cell-based assays.
- Inhibits Eg5 with an IC50 of 14 μM.
- High purity suitable for research applications.
- Cell-permeable for use in live-cell assays.
- Available in multiple pack sizes, including 100 MG.
- Useful for studying spindle assembly and mitotic progression.